Biofabrication of SDF-1 Functionalized 3D-Printed Cell-Free Scaffolds for Bone Tissue Regeneration

Functionalized mesoporous bioactive glass scaffolds for enhanced bone tissue regeneration

Mesoporous bioactive glass (MBG), which possesses excellent bioactivity, biocompatibility and osteoconductivity, has played an important role in bone tissue regeneration. However, it is difficult to prepare MBG scaffolds with high compressive strength for applications in bone regeneration; this difficulty has greatly hindered its development and use. To solve this problem, a simple powder proce...

Biofabrication of Tissue Scaffolds

3D Printed Scaffolds as a New Perspective for Bone Tissue Regeneration: Literature Review

Due to the high incidence of bone fractures in the population, it became necessary to produce scaffolds that are able to assist in tissue regeneration. It is necessary to find an appropriate balance between the mechanical and biological properties, in order to mimic the natural tissue, these properties are directly related to the architecture and their degree of porosity, as well as the size of...

Increased Osteogenic Potential of Pre-Osteoblasts on Three-Dimensional Printed Scaffolds Compared to Porous Scaffolds for Bone Regeneration

Background: One of the main challenges with conventional scaffold fabrication methods is the inability to control scaffold architecture. Recently, scaffolds with controlled shape and architecture have been fabricated using 3D-printing. Herein, we aimed to determine whether the much tighter control of microstructure of 3DP PLGA/β-TCP scaffolds is more effective in promoting osteogenesis than por...

Bone Regeneration with Cell-free Injectable Scaffolds

Hulsart Billström, G. 2017. Bone Regeneration with Cell-free Injectable Scaffolds. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1287. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9786-6. Bone is a remarkable multifunctional tissue with the ability to regenerate and remodel without generating any scar tissue. However, bone loss due to i...